A Physician-Scientist on Neurodegeneration

Dr. John Crary is a MD/PhD and board-certified neuropathologist at the Icahn School of Medicine at Mount Sinai. Dr. Crary is a leading physician-scientist whose work has redefined how brain diseases are diagnosed, from primary age-related tauopathy (PART) to chronic traumatic encephalopathy (CTE) and progressive supranuclear palsy (PSP).

We explore the evolving landscape of neuropathologies, breaking down how conditions like Alzheimer’s can be understood beyond just plaques and tangles, and examining what tauopathies mean for both patients and medical trainees. Dr. Crary also discusses the impact of concussions in sport, the role of Artificial Intelligence in brain research, and the challenges of bias in medical datasets.

Whether you’re a medical student, researcher, or simply curious about the brain, this episode offers a deep yet accessible look at the intersection of science, medicine, and technology in understanding neurodegeneration.